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    Unlocking the potential of exceptional life science technologies and entrepreneurs

    We fuel early stage life science startups that focus on R&D tools, platform technologies, and computational biology to solve today's roadblocks and allow for tomorrow's discoveries and therapeutics to thrive.

  • Tech+Bio is the Future

    We help grow the companies developing the tools to build that future.

     

    Phase Two Ventures is a seed venture fund based in San Diego investing in early-stage life science tools, platform technologies and computational biology to support the next generation of basic research, diagnostics, and therapeutics. We aim to discover and support diverse science entrepreneurs with backgrounds in multi-omics, bioengineering, synthetic biology, and cell & gene therapies. The firm was co-founded by entrepreneurs with years of operational experience and understand the nuances of taking early technology towards commercial success. We put that experience to work with pre-seed startups by providing capital, coaching, and support.

  • Portfolio

    Active and Prior* to launch of Phase Two Ventures

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    Andson Biotech

    Sample prep and data analytics solutions for mass spectrometry workflows.

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    Defined Bioscience

    Cell culture reagents to consistently grow stem cells and iPSC-derived tissue.

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    Lynx Biosciences

    Resolving cancer biology through integrated multi-omics.

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    NanoCellect Biomedical*

    Microfluidic cell sorting technology for single-cell cloning and genomics.

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    Arima Genomics*

    3D genomics provides information on both the sequence + structure of the genome.

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    Novoron Bioscience*

    Restoring the regenerative capacity of the brain and spinal cord.

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    ScholarNexus*

    Life Science startup accelerator.

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    Sweetspot Diabetes*

    A health data company focused on improving the use of data in the treatment of diabetes. Acquired by Dexcom

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    Mesa Biotech*

    A healthcare test and data company that provides infectious disease testing. Acquired by Thermo Fisher

  • Team

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    José Morachis

    Founder and Managing Partner

    Dr. Morachis has 15+ years of experience in life science tools and co-founding startups. He co-founded NanoCellect, a global leader in cell sorting technology, and Defined Bioscience for stem cell research. Currently, he serves on the Board of Directors at Defined Bioscience and Lynx Bio, focusing on novel immuno-oncology therapeutics. As managing partner of ScholarNexus, he co-founded Arima Genomics, a leading 3D genomics company. With a PhD from UCSD and postdoctoral research at UCSD's Laboratory of Bioresponsive Materials, Dr. Morachis contributed to nanotechnology and cancer research.

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    Will Alaynick

    Founder and Managing Partner

    Will is an accomplished biotech entrepreneur and executive. He has served on the Boards of NanoCellect, Arima Genomics, Defined Bioscience, and One4All Charitable Fund and has held roles as COO, VP International, and VP Business Development. With 30 peer-reviewed publications and two patents, Will has a strong R&D background, including a PhD in Biomedical Sciences from UC San Diego School of Medicine, The Salk Institute, and HHMI. Will's dynamic leadership and passion for biotechnology have made a significant impact in the industry.

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    Mark Nowakowski

    Venture Partner

    Mark has over 30 years of experience in molecular diagnostics and immunodiagnostics. He is a leader in lyophilization technologies, and microchannel diagnostic cartridge designs and currently CTO and Board Member of Argonaut Manufacturing. He founded and grew Lyogen before being acquired by Argonaut. He previously worked at Hybritech Incorporated, Biosite Diagnostics, FMC BioProducts, and Mesa Biotech with responsibilities including product design and manufacturing automation.

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    Eddie Rodriguez

    Venture Partner

    Eddie Rodriguez is a co-founder and partner at Teal Ventures, an early stage venture capital fund focused on disruptive healthcare innovation. He's a recognized corporate attorney with expertise in venture capital and M&A, having represented numerous startups and companies in various industries. Eddie has co-founded medical device and technology companies and is an active early stage investor. He holds a JD from Stanford Law School and a B.A. from the University of California, Los Angeles.

  • Advisory Team

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    Darlene Solomon

    Advisor

    Darlene is a highly esteemed technology and business executive, was elected to the National Academy of Engineering and named one of the Top 25 Women in Biotech by Healthcare Technology Report. With nearly four decades of experience, she served as Senior Vice President and Chief Technology Officer at Agilent Technologies from 2003 until July 2023, playing a pivotal role in transforming Agilent into a leading life sciences and healthcare company. Solomon led Agilent Research Laboratories and oversaw university relations, external research, and venture investments. She began her career as a research scientist at Hewlett-Packard Laboratories, eventually moving into leadership roles within Agilent post its spin-out from HP. Solomon holds a BS in chemistry from Stanford University, a doctorate in bioinorganic chemistry from MIT, and completed Stanford’s Executive Development Program. She is on the boards of Materion Corporation and Novanta, Inc., and has been recognized for her contributions to engineering and biotechnology.

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    Hong Cai

    Advisor

    Previously Founder/CEO of Mesa Biotech (acquired by Thermo Fisher). Dr. Hong Cai has more than 20 years of experience in the field of molecular biology and is the inventor of the technology used in Mesa Biotech’s platform. She spent 13 years as a principal investigator at Los Alamos National Laboratory, managing and leading projects for nucleic acid-based assays for forensic analysis, biothreat pathogen detection, and human disease diagnosis.

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    Yuhwa Lo

    Advisor

    Yuhwa Lo is a distinguished scientist and inventor known for his pioneering contributions in the field of microelectronics and nanotechnology. He is currently a professor at the University of California, San Diego (UCSD), where he holds the title of the Raytheon Endowed Chair in the Electrical and Computer Engineering Department. Dr. Lo has earned several prestigious awards and honors throughout his career and was named 2022 National Academy of Inventors (NAI) fellow, the highest professional distinction awarded to academic inventors.

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    David Yazdi

    Advisor

    David Yazdi is a scientist and entrepreneur, serving as the Co-Founder and CEO of Filtrous and Labifi, which are dedicated to supplying high-quality lab consumables and instrumentation to molecular and analytical laboratories. With a focus on biotech innovation, he has successfully created two biotech incubators. He received a BS in Biochemistry and Mathematics from UCLA.

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    Michael Weiner

    Advisor

    Michael P. Weiner, Ph.D., is CEO of AbbraTech. Dr Weiner is a serial scientific entrepreneur, having either founded or been one of the first scientists at several biotechnology companies, including: RainDance Technologies, 454 Life Sciences, Affomix, AxioMx, GnuBio and Encodia. His achievements have been recognized through prestigious awards, including Connecticut Entrepreneur of the Year and the Citetab Lifetime Achievement Award.

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    Bruce Cary

    Advisor

    Dr. Cary, co-founder of Mesa Biotech, is a visionary inventor driving rapid molecular tests. With expertise from Los Alamos National Laboratory, he led biodefense and pathogen detection projects. Mesa Biotech's success led to its acquisition by Thermo Fisher, cementing its industry leadership.

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